surgical excision followed by low dose rate radiotherapy in the management of resistant keloids
نویسندگان
چکیده
background depending on the cause, 40-90% of every deep dermis insult ends up in scar formation. several modalities have been suggested as a treatment but a high rate of recurrence is reported in most of those interventions. high dose radiotherapy has been shown to be effective in reducing the recurrence rate. this study tried to determine the effectiveness of low dose rate radiotherapy following surgical excision in treating resistant keloids. methods between january 2008 and april 2011, seventeen patients (mostly burn patients) with 26 keloids went through surgical resection followed by radiotherapy. a total dose of 15 gy in 5 fractions was administered to the areas of scar formation. results all patients were followed for at least 11 months (mostly for 20 months). no recurrence occurred. there was no complication or adverse effect. conclusion surgical excision followed by low dose postoperative radiotherapy was an efficient treatment for keloids that were resistant to many other modalities.
منابع مشابه
Surgical Excision Followed by Low Dose Rate Radiotherapy in the Management of Resistant Keloids
BACKGROUND Depending on the cause, 40-90% of every deep dermis insult ends up in scar formation. Several modalities have been suggested as a treatment but a high rate of recurrence is reported in most of those interventions. High dose radiotherapy has been shown to be effective in reducing the recurrence rate. This study tried to determine the effectiveness of low dose rate radiotherapy follow...
متن کاملSurgical Excision Followed by Low Dose Rate Radiotherapy in the Management of Resistant Keloids
BACKGROUND Depending on the cause, 40-90% of every deep dermis insult ends up in scar formation. Several modalities have been suggested as a treatment but a high rate of recurrence is reported in most of those interventions. High dose radiotherapy has been shown to be effective in reducing the recurrence rate. This study tried to determine the effectiveness of low dose rate radiotherapy followi...
متن کاملOutcomes of Surgical Excision and Brachytherapy in Intractable Keloids
BACKGROUND Keloids as unusual scars are injury remnants characterized by bizarre cosmetics and painful itching. This study assessed outcomes of surgical excision and brachytherapy in intractable keloids. METHODS Six patients with 10 keloid lesions were followed up. Surgical excision was done with 1-2 mm margin, and then radiotherapy was undertaken in 3 divided fractions on days 0, 1 and 2 ...
متن کاملPostoperative radiotherapy in the management of keloids
BACKGROUND The high recurrence rate following keloid resection has generated interest in adjuvant treatments for this disease. OBJECTIVE This study assesses keloid recurrence when treated with surgery and adjuvant radiotherapy. METHODS Retrospective analysis of resected keloids in patients referred to a Chilean radiation oncology centre between 2006 and 2013. Local recurrence was defined as...
متن کاملSurgical excision and immediate postoperative radiotherapy versus cryotherapy and intralesional steroids in the management of keloids: a prospective clinical trial.
OBJECTIVE To compare the efficacy and tolerability of surgical excision and radiotherapy with those of cryotherapy and intralesional steroid treatment of keloids. SUBJECTS AND METHODS Twenty-six patients with a total of 76 keloids were enrolled in this study. Nineteen patients with 44 keloids underwent surgical excision combined with immediate 12-Gy irradiation (group A) while the remaining 9...
متن کاملSurgical Excision and Immediate Postoperative Radiotherapy versus Cryotherapy and Intralesional Steroids in the Management of Keloids: A Prospective Clinical Trial
Objective: To compare the efficacy and tolerability of surgical excision and radiotherapy with those of cryotherapy and intralesional steroid treatment of keloids. Subjects and Methods: Twenty-six patients with a total of 76 keloids were enrolled in this study. Nineteen patients with 44 keloids underwent surgical excision combined with immediate 12-Gy irradiation (group A) while the remaining 9...
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عنوان ژورنال:
world journal of plastic surgeryجلد ۲، شماره ۲، صفحات ۸۱-۸۶
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